Ethanol → 4-(Aminomethyl)-1-methylpiperidin-4-ol

HRID 115941

Reaction equation

HRID 115941 reaction equation
[CH3:13][CH2:14][OH:15].[CH3:1][N:2]1[CH2:3][CH2:4][C:5]([OH:8])([CH2:9][N+:10]([O-:11])=[O:12])[CH2:6][CH2:7]1.[OH-:16].[OH-:18].[Pd+2:17]>>[CH3:1][N:2]1[CH2:3][CH2:4][C:5]([OH:8])([CH2:9][NH2:10])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2733771-Methyl-4-(nitromethyl)piperidin-4-ol

Product 1

HCID 64842624-(Aminomethyl)-1-methylpiperidin-4-ol

Sources & evidence

ORD record
ord-cc0bd28711124413aade891978e8d2e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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