HCID 11405563, compound → HCID 11269746, compound

Reaction equation

[NH:1]1[CH:5]=[CH:4][N:3]=[N:2]1.[N:6]1([C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][C:20]([N:23]4[CH2:27][C@H:26]([CH2:28]O)[O:25][C:24]4=[O:30])=[CH:19][C:18]=3[F:31])=[CH:13][N:12]=2)[CH:10]=[N:9][CH:8]=[N:7]1>>[N:6]1([C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][C:20]([N:23]4[CH2:27][C@H:26]([CH2:28][N:1]5[CH:5]=[CH:4][N:3]=[N:2]5)[O:25][C:24]4=[O:30])=[CH:19][C:18]=3[F:31])=[CH:13][N:12]=2)[CH:10]=[N:9][CH:8]=[N:7]1

Participants

Reactant 2

HCID 11405563HCID 11405563, compound

HCID 178418936HCID 178418936, compound

Product 1

HCID 11269746HCID 11269746, compound

Procedure

The same procedure as in Example 24 was conducted, except for adding 1,2,3-triazol and using the compound 17 as a starting material, to obtain the title compound.

Sources & evidence

ORD record: ord-29368400008c4e15b0a6ecc92b020715
Source dataset: uspto-grants-2010_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07816379B2

Reaction notes

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