2-Amino-5-(6-morpholin-4-ylpyridin-3-yl)thiophene-3-carboxamide → 2-{[6-Methyl-5-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl]amino}-5-(6-morpholin-4-ylpyridin-3-yl)thiophene-3-carboxamide
Reaction equation
[Cl:22][c:23]1[cH:24][cH:25][c:26]([CH:30]([C:31]([F:32])([F:33])[F:34])[OH:35])[c:27]([CH3:29])[n:28]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][n:12][c:13]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[cH:11][n:12][c:13]([N:16]3[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:23]1[cH:24][cH:25][c:26]([CH:30]([C:31]([F:32])([F:33])[F:34])[OH:35])[c:27]([CH3:29])[n:28]1Participants
3
Sources & evidence
- ORD record
- ord-36231cca697c4e88a5b57574540a4dfe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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