4'-Methyl-biphenyl-2-carboxylic acid-piperidin-4-ylamide → HCID 22995516, compound

Reaction equation

[NH:1]1[CH2:6][CH2:5][CH:4]([NH:7][C:8]([C:10]2[C:11]([C:16]3[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=3)=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:9])[CH2:3][CH2:2]1.[Br:23][CH2:24][CH2:25][CH2:26][C:27]([CH2:39][CH3:40])([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)[CH2:28][C:29]([O:31][CH3:32])=[O:30]>>[BrH:23].[CH2:39]([C:27]([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)([CH2:26][CH2:25][CH2:24][N:1]1[CH2:6][CH2:5][CH:4]([NH:7][C:8]([C:10]2[C:11]([C:16]3[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=3)=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:9])[CH2:3][CH2:2]1)[CH2:28][C:29]([O:31][CH3:32])=[O:30])[CH3:40]

Participants

Reactant 2

HCID 229956434'-Methyl-biphenyl-2-carboxylic acid-piperidin-4-ylamide

HCID 22995662HCID 22995662, compound

Product 1

HCID 22995516HCID 22995516, compound

Procedure

Prepared from 4′-methyl-biphenyl-2-carboxylic acid-piperidin-4-ylamide and methyl 5-bromo-2-ethyl-2-phenyl-pentanecarboxylate.

Sources & evidence

ORD record: ord-1f9a1eb5430d4ee096438269c66b4419
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06617325B1

Reaction notes

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