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Mafenide → HCID 58985681, compound

HRID 1169738
Notes
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Reaction equation

HRID 1169738 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5](I)=[CH:4][N:3]=1.[NH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([S:18]([NH2:21])(=[O:20])=[O:19])=[CH:14][CH:13]=1.CC1(C)C(C)(C)OB([C:30]2[S:31][CH:32]=[CH:33][CH:34]=2)O1>>[Cl:1][C:2]1[N:7]=[C:6]([NH:10][CH2:11][C:12]2[CH:13]=[CH:14][C:15]([S:18]([NH2:21])(=[O:19])=[O:20])=[CH:16][CH:17]=2)[C:5]([C:30]2[S:31][CH:32]=[CH:33][CH:34]=2)=[CH:4][N:3]=1
ParticipantsProcedureWorkupSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 3998MafenideHCID 2634382,4-Dichloro-5-iodopyrimidineHCID 107036284,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane

Product 1

HCID 58985681HCID 58985681, compound

Procedure

Preparation according to procedures 2 and 3 with the use of 2,4-dichloro-5-iodopyrimidine, 4-aminomethyl-benzenesulphonamide and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

Workup

  1. customPreparation

Sources & evidence

On this pageParticipantsProcedureWorkupSources & evidenceReaction notes
ORD record
ord-f0ec42b659814b1eb5389f317207bcf6
Source dataset
uspto-grants-2010_11
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US07825128B2

Reaction notes

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