2,4-Dichloro-5-iodopyrimidine → HCID 58985786, compound
Reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5](I)=[CH:4][N:3]=1.[NH2:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([CH2:17][NH:18][C:19](=[O:27])[C:20]1[CH:25]=[CH:24][C:23]([CH3:26])=[CH:22][CH:21]=1)=[O:16].CC1(C)C(C)(C)OB([C:36]2[S:37][CH:38]=[CH:39][CH:40]=2)O1>>[Cl:1][C:2]1[N:7]=[C:6]([NH:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([CH2:17][NH:18][C:19](=[O:27])[C:20]2[CH:25]=[CH:24][C:23]([CH3:26])=[CH:22][CH:21]=2)=[O:16])[C:5]([C:36]2[S:37][CH:38]=[CH:39][CH:40]=2)=[CH:4][N:3]=1Participants
4
Procedure
Preparation according to procedures 2 and 3 with the use of 2,4-dichloro-5-iodopyrimidine, N-[(3-amino-propylcarbamoyl)-methyl]-4-methyl-benzamide and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.
Workup
- customPreparation