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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 117639Generated: October 26, 2026

1-(Trimethylsilyl)pyrrolidin-2-one → 5-{5-[2,6-dichloro-4-(4,5-dihydro-3H-pyrrol-2-yl)phenoxy]pentyl}-3-methylisoxazole

https://huagongshe.com/reaction/117639

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Trimethylsilyl)pyrrolidin-2-oneHCID 84461—
Reactant5-[5-(2,6-Dichloro-4-iodophenoxy)pentyl]-3-methylisoxazoleHCID 10320995—
ReactantButyllithiumHCID 178418339—
Product5-{5-[2,6-dichloro-4-(4,5-dihydro-3H-pyrrol-2-yl)phenoxy]pentyl}-3-methylisoxazoleHCID 515436—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-f33f7b4965fb4d718d5a54559b0f5ce0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)