Ethylamine → N-ethyl-2-nitrobenzene-1-sulfonamide
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10](Cl)(=[O:12])=[O:11])([O-:3])=[O:2].[CH2:14]([NH2:16])[CH3:15]>O>[CH2:14]([NH:16][S:10]([C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2])(=[O:12])=[O:11])[CH3:15]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2-nitrobenzenesulfonyl chloride (10 g) is added portion-wise to 70% ethylamine in water at 0-5° C., maintaining the temperature. It is stirred for 15 minutes until completing the transformation. Water (80 mL) is added, maintaining the temperature. It is stirred for 30 minutes. It is filtered, washed and dried, obtaining 8.97 g of N-ethyl-2-nitrobenzenesulfonamide.
Workup
- temperaturemaintaining the temperature
- temperaturemaintaining the temperature
- stirringIt is stirred for 30 minutes
- filtrationIt is filtered
- washwashed
- customdried
Sources & evidence
- ORD record
- ord-19a61b390a364cd58f8acbef0d875aa7
- Source dataset
- uspto-grants-2010_11
- Patent number
- US07842821B2
Reaction notes
Loading…