3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline → N-(3-{3-[4-(2-Methyl-quinolin-5-yl)-piperazin-1-yl]-propyl}-phenyl)-methanesulfonamide
Reaction equation
O=[CH:2][CH2:3][CH2:4][C:5]1[CH:6]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:9][CH:10]=1.[CH3:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][C:23]=2[N:27]2[CH2:32][CH2:31][N:30](CCC3C=C(C=CC=3)N)[CH2:29][CH2:28]2)[N:18]=1>>[CH3:16][C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[CH:20][CH:21]=[CH:22][C:23]=2[N:27]2[CH2:32][CH2:31][N:30]([CH2:2][CH2:3][CH2:4][C:5]3[CH:6]=[C:7]([NH:11][S:12]([CH3:15])(=[O:14])=[O:13])[CH:8]=[CH:9][CH:10]=3)[CH2:29][CH2:28]2)[N:18]=1Participants
3
Procedure
The title compound was prepared from N-[3-(3-oxo-propyl)-phenyl]-methanesulfonamide and of 2-methyl-5-(1-piperazinyl)quinoline (D3) according to the methods in Description 4 and Description 5.
Sources & evidence
- ORD record
- ord-e23afaa4991c4e8fac7bfe956d1dd602
- Source dataset
- uspto-grants-2007_10