Carbamic chloride, N-methyl-N-phenyl- → HCID 69520171, compound

Reaction equation

[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5][C:6]2=[O:11].[CH3:12][N:13]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:14](Cl)=[O:15]>>[O:11]=[C:6]1[C:7]2[C:3](=[C:2]([O:1][C:14](=[O:15])[N:13]([CH3:12])[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:10]=[CH:9][CH:8]=2)[CH2:4][CH2:5]1

Participants

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-

HCID 5905474-Hydroxy-1-indanone

Product 1

HCID 69520171HCID 69520171, compound

Procedure

The title product was prepared from 4-hydroxyindanone and N-methyl-N-phenylcarbamoyl chloride. The crude product was subjected to preparative HPLC. (77%, light yellow oil). HPLC-MS: m/z=282.1 (M+1); Rt: 3.54 min.

Sources & evidence

ORD record: ord-ad627a0dd8ca40a3ab51b13446c5e8c2
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07279470B2

Reaction notes

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