6-Aminoquinoline → N-(4-nitrophenyl)-N'-[quinolin-6-yl]urea

HRID 1181462

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[CH:5]2.[N+:12]([C:15]1[CH:20]=[CH:19][C:18]([N:21]=[C:22]=[O:23])=[CH:17][CH:16]=1)([O-:14])=[O:13]>>[N+:12]([C:15]1[CH:16]=[CH:17][C:18]([NH:21][C:22]([NH:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[N:8]=[CH:7][CH:6]=[CH:5]3)=[O:23])=[CH:19][CH:20]=1)([O-:14])=[O:13]

Participants

Reactant 2

HCID 113736-Aminoquinoline

HCID 66012Benzene, 1-isocyanato-4-nitro-

Product 1

HCID 69522714N-(4-nitrophenyl)-N'-[quinolin-6-yl]urea

Procedure

Prepared from 6-aminoquinoline and 4-nitrophenyl isocyanate. m/z (ES+) 309 (M+H)+.

Sources & evidence

ORD record: ord-fd6c82876edd4f9bbaeb5dfea70bc07e
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07285563B2

Linked notes

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