1-(Bromomethyl)naphthalene → 4-(Bromomethyl)-6-chloroquinoline

HRID 1181841

Reaction equation

HRID 1181841 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2[CH:12]=O.[Br:14]CC1C2C(=CC=CC=2)C=CC=1>>[Br:14][CH2:12][C:5]1[C:4]2[C:9](=[CH:10][CH:11]=[C:2]([Cl:1])[CH:3]=2)[N:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 1378441-(Bromomethyl)naphthaleneHCID 31460316-Chloroquinoline-4-carbaldehyde

Product 1

HCID 589809024-(Bromomethyl)-6-chloroquinoline

Procedure

4-(Bromomethyl)-6-chloroquinoline was prepared from 6-chloroquinoline-4-carbaldehyde following the procedure described in the preparation of 1-(bromomethyl)naphthalene.

Sources & evidence

ORD record
ord-f11641ce262144e59ecd4f4c2367a048
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Linked notes

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