Ethanol → Ethyl 5-amino-4-oxopentanoate--hydrogen chloride (1/1)

HRID 1181995

Reaction equation

[ClH:1].[NH2:2][CH2:3][C:4](=[O:10])[CH2:5][CH2:6][C:7]([OH:9])=[O:8].[CH2:11](O)[CH3:12]>>[ClH:1].[NH2:2][CH2:3][C:4](=[O:10])[CH2:5][CH2:6][C:7]([O:9][CH2:11][CH3:12])=[O:8]

Participants

Reactant 2

HCID 702Ethanol

HCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 22253145Ethyl 5-amino-4-oxopentanoate--hydrogen chloride (1/1)

Procedure

From ethanol (6.0 ml) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol) at 70° C. The reaction was complete after 2 h. The yield was 1.0 g (85%).

Workup

customat 70° C

Sources & evidence

ORD record: ord-7ea97a01542f429fa59b21ea3b67805f
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07287646B2

Linked notes

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