3,5-Dibromopyridine → 3-Bromo-5-(4-(trifluoromethyl)phenyl)pyridine
Reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Br:8])[CH:7]=1.[F:9][C:10]([F:21])([F:20])[C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1>>[Br:8][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([C:14]2[CH:15]=[CH:16][C:11]([C:10]([F:21])([F:20])[F:9])=[CH:12][CH:13]=2)[CH:7]=1Participants
3
Procedure
Prepared according to the procedure described in Example 1, Step 10, using 3,5-dibromo-pyridine and 4-(trifluoromethyl)-phenylboronic acid.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-28b22f64a18845cfa873568acfba8c5f
- Source dataset
- uspto-grants-2014_03
- Patent number
- US08664220B2
Reaction notes
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