4-Hydroxyphenylpyruvic Acid → 8-benzyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one
Reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](=O)[C:10]([OH:12])=O)=[CH:4][CH:3]=1.[CH2:14]([C:21]1[C:22]([NH2:33])=[N:23][CH:24]=[C:25]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[N:26]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([C:21]1[NH:26][C:25]([C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)=[CH:24][N:23]2[C:10](=[O:12])[C:9]([CH2:8][C:5]3[CH:4]=[CH:3][C:2]([OH:1])=[CH:7][CH:6]=3)=[N:33][C:22]=12)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1Participants
3
Procedure
Synthesized using method A with 3-(4-hydroxyphenyl)-2-oxopropanoic acid and 3-benzyl-5-phenylpyrazin-2-amine as starting materials. Exact mass calculated for C26H22N3O2+ m/z+408.17, found m/z+408.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-b989062e4f4b4bf49454348f486ed5b9