Isopropylamine → 3-Bromo-n-isopropylimidazo[1,2-a]pyrazin-8-amine

HRID 1186465Notes

Reaction equation

HRID 1186465 reaction equation
[Br:1][C:2]1[N:6]2[CH:7]=[CH:8][N:9]=[C:10](Cl)[C:5]2=[N:4][CH:3]=1.[CH:12]([NH2:15])([CH3:14])[CH3:13]>>[Br:1][C:2]1[N:6]2[CH:7]=[CH:8][N:9]=[C:10]([NH:15][CH:12]([CH3:14])[CH3:13])[C:5]2=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 100598493-Bromo-8-chloroimidazo[1,2-a]pyrazine

Product 1

HCID 210709143-Bromo-n-isopropylimidazo[1,2-a]pyrazin-8-amine

Procedure

(3-Bromo-imidazo[1,2-a]pyrazin-8-yl)-isopropyl-amine was prepared by a process analogous to that described in Example 2 starting from 3-bromo-8-chloro-imidazo[1,2-a]pyrazine and isopropylamine.

Sources & evidence

ORD record
ord-b4a3fe7d151840bf8cde88ffd96bc06f
Source dataset
uspto-grants-2014_03
Patent number
US08673905B2

Reaction notes

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