HCID 86689304, compound → HCID 86689999, compound

Reaction equation

O([C:9]1[CH:18]=[CH:17][C:16]2[CH2:15][CH2:14][CH2:13][CH2:12][C:11]=2[C:10]=1[N+:19]([O-:21])=[O:20])S(C(F)(F)F)(=O)=O.[NH2:22][C:23]1[CH:31]=[CH:30][CH:29]=[C:28]2[C:24]=1[CH:25]=[CH:26][N:27]2[CH2:32][O:33][CH2:34][CH2:35][Si:36]([CH3:39])([CH3:38])[CH3:37]>>[N+:19]([C:10]1[C:11]2[CH2:12][CH2:13][CH2:14][CH2:15][C:16]=2[CH:17]=[CH:18][C:9]=1[NH:22][C:23]1[CH:31]=[CH:30][CH:29]=[C:28]2[C:24]=1[CH:25]=[CH:26][N:27]2[CH2:32][O:33][CH2:34][CH2:35][Si:36]([CH3:39])([CH3:38])[CH3:37])([O-:21])=[O:20]

Participants

Reactant 2

HCID 86689304HCID 86689304, compound

HCID 86690000HCID 86690000, compound

Product 1

HCID 86689999HCID 86689999, compound

Procedure

1-Nitro-5,6,7,8-tetrahydronaphthalen-2-yl triflate and 4-amino-1-[2-(trimethylsilyl)ethoxymethyl]-1H-indole were used in a process similar to Example 1(1) to give the titled compound.

Sources & evidence

ORD record: ord-901049435fcf43009502ab775f7d71ed
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08673915B2

Reaction notes

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