Acetic Acid → phenyl-(2-(1-Boc-4-piperidinylamino)phenyl) carbinol

HRID 118723

Reaction equation

HRID 118723 reaction equation
[C:16](=[O:17])([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[N:23]1[CH2:24][CH2:25][C:26](=[O:29])[CH2:27][CH2:28]1.[C:34]([BH3-:35])#[N:36].[CH3:30][C:31](=[O:32])[OH:33].[CH3:38][OH:39].[NH2:1][c:2]1[c:3]([CH:4]([c:5]2[cH:6][cH:7][cH:8][cH:9][cH:10]2)[OH:11])[cH:12][cH:13][cH:14][cH:15]1.[Na+:37]>>[NH:1]([c:2]1[c:3]([CH:4]([c:5]2[cH:6][cH:7][cH:8][cH:9][cH:10]2)[OH:11])[cH:12][cH:13][cH:14][cH:15]1)[CH:26]1[CH2:25][CH2:24][N:23]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:28][CH2:27]1

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 887MethanolHCID 923Sodium ionHCID 2708102-AminobenzhydrolHCID 498716Cyano-borohydrideHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 57083091phenyl-(2-(1-Boc-4-piperidinylamino)phenyl) carbinol

Sources & evidence

ORD record
ord-83288c09d03844109368cea207d9d89b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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