1,3-Diacetylbenzene → alpha1,alpha3-Dimethyl-1,3-benzenedimethanol

HRID 1198277Notes

Reaction equation

HRID 1198277 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10](=[O:12])[CH3:11])[CH:5]=1)(=[O:3])[CH3:2].[BH4-].[Na+]>>[CH3:11][CH:10]([C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([CH:1]([CH3:2])[OH:3])[CH:5]=1)[OH:12]

Participants

3

Reactant 2

HCID 232291,3-DiacetylbenzeneHCID 4311764Sodium borohydride

Product 1

HCID 15148377alpha1,alpha3-Dimethyl-1,3-benzenedimethanol

Procedure

This mixture of stereoisomers was prepared from 1,3-diacetylbenzene by reduction with sodium borohydride as described above for the para stereoisomers. The mixture of stereoisomers was isolated as a semisolid. It appeared as a single spot on TLC and as a single peak on VPC.

Workup

  1. additionThis mixture of stereoisomers
  2. additionThe mixture of stereoisomers
  3. customwas isolated as a semisolid

Sources & evidence

ORD record
ord-828293c7f29e4075b17cc23d840ed7d7
Source dataset
uspto-grants-1994_01
Patent number
US05280096

Reaction notes

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