HCID 13854275, compound → 2,2-Dimethyl-3-(6-phenoxypyridin-2-yl)methoxypropan-1-al
Reaction equation
[CH3:1][C:2]([CH3:21])([CH2:5][O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:9]=1)[CH2:3][OH:4]>C(OCC)C>[CH3:1][C:2]([CH3:21])([CH2:5][O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[N:9]=1)[CH:3]=[O:4]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
2,2-Dimethyl-3-(6-phenoxypyridin-2-yl)methoxypropan-1-ol was reacted according to the procedure set out in Example 6. The crude product was subject to column chromatography on silica gel using petroleum ether (boiling range 40°-60° C.) containing 20% by volume diethylether as eluent, to give 2,2-dimethyl-3-(6-phenoxypyridin-2-yl)methoxypropan-1-al.
Sources & evidence
- ORD record
- ord-d25e5772d8fd47a68209393588e31d53
- Source dataset
- uspto-grants-1990_02