Dichloromethane → Tert-butyl 3-(fluoromethyl)pyrrolidine-1-carboxylate
Reaction equation
[C:14](=[O:15])([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[N:21]1[CH2:22][CH:23]([CH2:26][OH:27])[CH2:24][CH2:25]1.[CH3:28][O:29][CH2:30][CH2:31][N:32]([S:33]([F:34])([F:35])[F:36])[CH2:37][CH2:38][O:39][CH3:40].[Cl:41][CH2:42][Cl:43].[F:1][CH:2]1[CH2:3][CH2:4][N:5]([C:6]([O:7][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:12])[CH2:13]1>>[F:1][CH2:26][CH:23]1[CH2:22][N:21]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:25][CH2:24]1Participants
5
Sources & evidence
- ORD record
- ord-3409cf337fbd42659477a4470ace5d34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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