4-bromo-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-1-(pyridin-2-ylmethyl)-1,3-dihydro-2H-indol-2-one → 4-bromo-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-3-(hydroxymethyl)-1-(Pyridin-2-ylmethyl)-1,3-dihydro-2H-indol-2-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:6][c:7]2[c:8]1[CH:9]([c:10]1[c:11]([OH:12])[cH:13][c:14]3[c:19]([cH:20]1)[O:18][CH2:17][O:15]3)[C:5](=[O:16])[N:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26].[Br:27][c:28]1[c:29]2[c:33]([cH:34][cH:35][cH:36]1)[N:32]([CH2:37][c:38]1[n:39][cH:40][cH:41][cH:42][cH:43]1)[C:31](=[O:44])[CH:30]2[c:45]1[c:46]([OH:54])[cH:47][c:48]2[c:49]([cH:53]1)[CH2:50][CH2:51][O:52]2>>[CH2:5]([OH:16])[C:30]1([c:45]2[c:46]([OH:54])[cH:47][c:48]3[c:49]([cH:53]2)[CH2:50][CH2:51][O:52]3)[c:29]2[c:28]([Br:27])[cH:36][cH:35][cH:34][c:33]2[N:32]([CH2:37][c:38]2[n:39][cH:40][cH:41][cH:42][cH:43]2)[C:31]1=[O:44]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-982703be3bc94b2fb1dad2c388996b4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
- DOI