Ethyl 2-oxocyclohexanecarboxylate → Ethyl 3-bromo-2-oxocyclohexanecarboxylate
Reaction equation
[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][C:7]1=[O:12])=[O:5])[CH3:2].[Br:13]C1CC(C(C)C)CCC1=O>>[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][CH2:9][CH:8]([Br:13])[C:7]1=[O:12])=[O:5])[CH3:2]Participants
3
Procedure
The bromination of 2-oxo-cyclohexane carboxylic acid ethyl ester takes place in a manner similar to that described above for the preparation of 2-bromo-4-isopropyl-cyclohexanone. The title compound is reacted as a crude product without further characterization.
Sources & evidence
- ORD record
- ord-37fb364ca93b408f8103ecfca7b9d4ae
- Source dataset
- uspto-grants-2010_06
- Patent number
- US07727979B2
Reaction notes
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