Ethyl 4-oxocyclohexanecarboxylate → Ethyl 3-bromo-4-oxocyclohexane-1-carboxylate

HRID 12044

Reaction equation

HRID 12044 reaction equation
[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][C:9](=[O:12])[CH2:8][CH2:7]1)=[O:5])[CH3:2].[Br:13]C1CC(C(C)C)CCC1=O>>[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][C:9](=[O:12])[CH:8]([Br:13])[CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 317638Ethyl 4-oxocyclohexanecarboxylateHCID 627080672-Bromo-4-isopropyl-cyclohexanone

Product 1

HCID 12917737Ethyl 3-bromo-4-oxocyclohexane-1-carboxylate

Procedure

The bromination of 4-oxo-cyclohexane carboxylic acid ethyl ester takes place in a manner similar to that described above for the preparation of 2-bromo-4-isopropyl-cyclohexanone. The title compound is reacted as a crude product without further characterization.

Sources & evidence

ORD record
ord-aa5614f3adf74aaeaa8e0d65a3012e4f
Source dataset
uspto-grants-2010_06
Patent number
US07727979B2

Linked notes

Loading…