Methanol → 2-Chloro-6-methoxy-4-(trifluoromethyl)pyridine

Reaction equation

[CH3:15][OH:16].[CH3:17][OH:18].[Cl:1][c:2]1[n:3][c:4]([Cl:12])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Na+:14].[OH-:13]>>[Cl:1][c:2]1[n:3][c:4]([O:13][CH3:15])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

Reactant 4

HCID 887Methanol2×

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 5209682,6-Dichloro-4-(trifluoromethyl)pyridine

Product 1

HCID 568323142-Chloro-6-methoxy-4-(trifluoromethyl)pyridine

Sources & evidence

ORD record: ord-8f3228610d6d4241a3493141429921ea
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…