2-(7-Amino-8-methoxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-N-methyl-acetamide → 2-[5-Chloro-2-(8-methoxy-3-methylcarbamoylmethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino)-pyrimidin-4-ylamino]-N-ethyl-3-fluoro-benzamide
Reaction equation
[Cl:20][c:21]1[n:22][cH:23][c:24]([Cl:40])[c:25]([NH:27][c:28]2[c:29]([C:30](=[O:31])[NH:32][CH2:33][CH3:34])[cH:35][cH:36][cH:37][c:38]2[F:39])[n:26]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:16][c:17]1[O:18][CH3:19])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH:14][CH3:15])[CH2:9][CH2:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:16][c:17]1[O:18][CH3:19])[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH:14][CH3:15])[CH2:9][CH2:10]2)[c:21]1[n:22][cH:23][c:24]([Cl:40])[c:25]([NH:27][c:28]2[c:29]([C:30](=[O:31])[NH:32][CH2:33][CH3:34])[cH:35][cH:36][cH:37][c:38]2[F:39])[n:26]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-632c59f3f9314d00a8e4603b860a0491
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)