Dichloromethane → 4-(2,3,5,6-Tetrafluoro-pyridin-4-yl)-morpholine

Reaction equation

[CH2:12]1[CH2:13][O:14][CH2:15][CH2:16][NH:17]1.[Cl:18][CH2:19][Cl:20].[F:1][c:2]1[c:3]([F:11])[c:4]([F:10])[c:5]([F:9])[c:6]([F:8])[n:7]1>>[F:1][c:2]1[c:3]([F:11])[c:4]([N:17]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]([F:9])[c:6]([F:8])[n:7]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 8083Morpholine

HCID 69690Pentafluoropyridine

Product 1

HCID 674918494-(2,3,5,6-Tetrafluoro-pyridin-4-yl)-morpholine

Sources & evidence

ORD record: ord-62c541bc20ae44bd89e9aad61cca290b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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