(4-Fluoro-2-methylphenyl)boronic acid → 4-(4-Fluoro-2-methyl-phenyl)-6-(2-fluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([S:18][CH3:19])[n:5][c:6]([NH:10][c:11]2[c:12]([F:17])[cH:13][cH:14][cH:15][cH:16]2)[c:7]1[CH:8]=[O:9].[F:20][c:21]1[cH:22][c:23]([CH3:30])[c:24]([B:27]([OH:28])[OH:29])[cH:25][cH:26]1>>[c:2]1(-[c:24]2[c:23]([CH3:30])[cH:22][c:21]([F:20])[cH:26][cH:25]2)[n:3][c:4]([S:18][CH3:19])[n:5][c:6]([NH:10][c:11]2[c:12]([F:17])[cH:13][cH:14][cH:15][cH:16]2)[c:7]1[CH:8]=[O:9]Participants
3
Sources & evidence
- ORD record
- ord-4509c60638cc4fc5ad81c43e0ab27584
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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