1-Fluoro-3-isocyanato-5-(trifluoromethyl)benzene → 3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)-ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Reaction equation
[F:20][c:21]1[cH:22][c:23]([N:31]=[C:32]=[O:33])[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1.[NH2:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:17](=[O:18])[NH2:19])[nH:10][c:11]3[n:12][cH:13][cH:14][cH:15][c:16]23)[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:17](=[O:18])[NH2:19])[nH:10][c:11]3[n:12][cH:13][cH:14][cH:15][c:16]23)[cH:6][cH:7]1)[C:32]([NH:31][c:23]1[cH:22][c:21]([F:20])[cH:26][c:25]([C:27]([F:28])([F:29])[F:30])[cH:24]1)=[O:33]Participants
3
Sources & evidence
- ORD record
- ord-a08f075816364f95ae64cd3c6a5c2aec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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