Dichloromethane → 4-(2-Tert-butoxycarbonylaminoethyl)piperidine-1-carboxamide

HRID 1228294

Reaction equation

HRID 1228294 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][CH:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1.[CH3:17][Si:18]([CH3:19])([CH3:20])[N:21]=[C:22]=[O:23].[Cl:24][CH2:25][Cl:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][CH:11]1[CH2:12][CH2:13][N:14]([C:22]([NH2:21])=[O:23])[CH2:15][CH2:16]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 70696Trimethylsilyl isocyanateHCID 15018494-(2-Aminoethyl)piperidine, 4-BOC protected

Product 1

HCID 219309854-(2-Tert-butoxycarbonylaminoethyl)piperidine-1-carboxamide

Sources & evidence

ORD record
ord-27126aa354a5407cab11bbadd1f6d625
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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