Potassium Cation → 4-[4-(7-Chloro-imidazo[1,2-a]pyridin-3-yl)-phenyl]-N-(3-trifluoromethyl-phenyl)-butyramide

HRID 1228869

Reaction equation

HRID 1228869 reaction equation
[C:43](=[O:44])([O-:45])[O-:46].[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[cH:10][cH:11][c:12]([CH2:15][CH2:16][CH2:17][C:18](=[O:19])[NH:20][c:21]3[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]3)[cH:13][cH:14]2)[O:31]1.[Cl:32][c:33]1[cH:34][c:35]2[n:36]([cH:37][cH:38]1)[c:39]([I:42])[cH:40][n:41]2.[Cl:56][CH2:57][Cl:58].[K+:47].[K+:48].[O:49]1[CH2:50][CH2:51][O:52][CH2:53][CH2:54]1.[OH2:55]>>[c:9]1(-[c:39]2[n:36]3[c:35]([cH:34][c:33]([Cl:32])[cH:38][cH:37]3)[n:41][cH:40]2)[cH:10][cH:11][c:12]([CH2:15][CH2:16][CH2:17][C:18](=[O:19])[NH:20][c:21]2[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]2)[cH:13][cH:14]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 574976977-Chloro-3-iodoimidazo[1,2-a]pyridineHCID 685460734-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-N-(3-trifluoromethyl-phenyl)-butyramide

Product 1

HCID 685428324-[4-(7-Chloro-imidazo[1,2-a]pyridin-3-yl)-phenyl]-N-(3-trifluoromethyl-phenyl)-butyramide

Sources & evidence

ORD record
ord-55ad7053d6f043e0987fe2fa0f67e32b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Linked notes

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