Dichloromethane → Methyl 6-amino-4-(chroman-6-yl)-5-formyl-2-methylnicotinate
Reaction equation
[Cl:36][CH2:37][Cl:38].[NH2:1][c:2]1[n:3][c:4]([CH3:24])[c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10](-[c:14]2[cH:15][c:16]3[c:21]([cH:22][cH:23]2)[O:20][CH2:19][CH2:18][CH2:17]3)[c:11]1[CH2:12][OH:13].[O:25]=[Cr:26]([Cl:27])([O-:28])=[O:29].[nH+:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[NH2:1][c:2]1[n:3][c:4]([CH3:24])[c:5]([C:6](=[O:7])[O:8][CH3:9])[c:10](-[c:14]2[cH:15][c:16]3[c:21]([cH:22][cH:23]2)[O:20][CH2:19][CH2:18][CH2:17]3)[c:11]1[CH:12]=[O:13]Participants
5
Sources & evidence
- ORD record
- ord-97855e4b258c44ba98d92558020b2874
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…