Bicarbonate Ion → 2-(3-bromo-1H-pyrrolo[2,3-b]pyridin-5-yl)isoindoline-1,3-dione

Reaction equation

[Br:1][Br:2].[Cl:41][CH2:42][Cl:43].[Na+:33].[Na+:34].[Na+:35].[O-:29][C:30]([OH:31])=[O:32].[O-:36][S:37]([O-:38])(=[S:39])=[O:40].[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1.[nH:3]1[cH:4][cH:5][c:6]2[c:7]1[n:8][cH:9][c:10]([N:12]1[C:13](=[O:22])[c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]3[C:20]1=[O:21])[cH:11]2>>[Br:1][c:5]1[cH:4][nH:3][c:7]2[c:6]1[cH:11][c:10]([N:12]1[C:13](=[O:22])[c:14]3[cH:15][cH:16][cH:17][cH:18][c:19]3[C:20]1=[O:21])[cH:9][n:8]2

Participants

Reactant 7

HCID 769Bicarbonate Ion

HCID 923Sodium Ion3×

HCID 1049Pyridine

HCID 1084Thiosulfate ion

HCID 6344Dichloromethane

HCID 24408Bromine

HCID 591286702-(1H-pyrrolo[2,3-b]pyridin-5-yl)isoindoline-1,3-dione

Product 1

Sources & evidence

ORD record: ord-64a14c34de0e487e949f3aa9b80ebe2d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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