4-[(3,4-Difluorophenyl)methyl]piperidine → 2-[4-(3,4-Difluoro-benzyl)-piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide
Reaction equation
[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]2)[cH:12][cH:13][c:14]1[F:15].[O:16]=[c:17]1[o:18][c:19]2[c:20]([nH:21]1)[cH:22][cH:23][c:24]([NH:26][C:27]([C:28](=[O:29])[OH:30])=[O:31])[cH:25]2>>[F:1][c:2]1[cH:3][c:4]([CH2:5][CH:6]2[CH2:7][CH2:8][N:9]([C:28]([C:27]([NH:26][c:24]3[cH:23][cH:22][c:20]4[c:19]([o:18][c:17](=[O:16])[nH:21]4)[cH:25]3)=[O:31])=[O:29])[CH2:10][CH2:11]2)[cH:12][cH:13][c:14]1[F:15]Participants
3
Sources & evidence
- ORD record
- ord-12039b994bab4a3997c75f5e637b4d3f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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