Methanol → 4-[5-Amino-1-(2-fluoro-4-trifluoromethyl-phenyl)-1H-[1,2,3]triazol-4-yl]-phenol

Reaction equation

[B:26]([Br:27])([Br:28])[Br:29].[CH3:30][OH:31].[Cl:34][CH2:35][Cl:36].[F:1][c:2]1[c:3](-[n:12]2[n:13][n:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([O:24][CH3:25])[cH:22][cH:23]3)[c:16]2[NH2:17])[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[Na+:33].[OH-:32].[OH2:37]>>[F:1][c:2]1[c:3](-[n:12]2[n:13][n:14][c:15](-[c:18]3[cH:19][cH:20][c:21]([OH:24])[cH:22][cH:23]3)[c:16]2[NH2:17])[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

Reactant 7

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 252156773-(2-Fluoro-4-trifluoromethyl-phenyl)-5-(4-methoxy-phenyl)-3H-[1,2,3]triazol-4-ylamine

Product 1

Sources & evidence

ORD record: ord-86b027fbc4d84019897e0e3a4cd12959
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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