HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 123737Generated: October 23, 2026
2-Amino-2-methyl-1,3-propanediol → 2-(1-hydroxymethyl-1-methyl-2-hydroxyethyl amino)-4-(4-fluoro-2-methylphenyl)-8-(2,6-difluorophenyl)-8H-pyrido[2,3-d]pyrimidin-7-one
https://huagongshe.com/en/reaction/123737
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Amino-2-methyl-1,3-propanediol | HCID 1531 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 8-(2,6-difluoro-phenyl)-4-(4-fluoro-2-methyl-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one | HCID 59639554 | — |
| Product | 2-(1-hydroxymethyl-1-methyl-2-hydroxyethyl amino)-4-(4-fluoro-2-methylphenyl)-8-(2,6-difluorophenyl)-8H-pyrido[2,3-d]pyrimidin-7-one | HCID 59639563 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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| ORD ID | ord-e85fef62a5fe4e9284982ef4df1ddd32 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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