Potassium Cation → 4-(4-Chlorobenzyl)-1-(1H-pyrazolo[3,4-b]pyridin-4-yl)-piperidin-4-ylamine

Reaction equation

[CH2:1]([O:2][C:3](=[O:4])[c:6]1[c:7]([N:15]2[CH2:16][CH2:17][C:18]([CH2:21][c:22]3[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]3)([NH2:29])[CH2:19][CH2:20]2)[c:8]2[c:9]([n:10][cH:11]1)[nH:12][n:13][cH:14]2)[CH3:5].[K+:32].[OH-:31].[OH2:30]>>[cH:6]1[c:7]([N:15]2[CH2:16][CH2:17][C:18]([CH2:21][c:22]3[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]3)([NH2:29])[CH2:19][CH2:20]2)[c:8]2[c:9]([n:10][cH:11]1)[nH:12][n:13][cH:14]2

Participants

Reactant 4

HCID 813Potassium Cation

HCID 961Hydroxide

HCID 962Water

HCID 578991924-[4-amino-4-(4-chlorobenzyl)-piperidin-1-yl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester

Product 1

HCID 451422584-(4-Chlorobenzyl)-1-(1H-pyrazolo[3,4-b]pyridin-4-yl)-piperidin-4-ylamine

Sources & evidence

ORD record: ord-278d016642cb43e6887ed40dc8148b2d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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