1-(5-Cyano-2-pyridinyl)-4-piperidinecarboxylic acid → 6-[1-[3-(4-Chlorophenyl)-1-[1-(5-cyano-2-pyridinyl)piperidine-4-carbonyl]piperidin-4-yl]ethylamino]pyridine-3-carbonitrile
Reaction equation
[C:61](#[N:62])[c:63]1[cH:64][cH:65][c:66]([N:69]2[CH2:70][CH2:71][CH:72]([C:75](=[O:76])[OH:77])[CH2:73][CH2:74]2)[n:67][cH:68]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:6]2[CH:7]([CH2:8][O:9][c:10]3[cH:11][cH:12][c:13]([Cl:14])[cH:15][n:16]3)[CH2:17][CH2:18][N:19]([C:20]([c:21]3[cH:22][cH:23][c:24](-[c:25]4[o:26][n:27][c:28]([CH3:29])[n:30]4)[cH:31][cH:32]3)=[O:33])[CH2:34]2)[cH:35][cH:36]1.[Cl:37][c:38]1[cH:39][cH:40][c:41]([CH:44]2[CH2:45][NH:46][CH2:47][CH2:48][CH:49]2[CH:50]([CH3:51])[NH:52][c:53]2[n:54][cH:55][c:56]([C:57]#[N:58])[cH:59][cH:60]2)[cH:42][cH:43]1>>[Cl:37][c:38]1[cH:39][cH:40][c:41]([CH:44]2[CH2:45][N:46]([C:75]([CH:72]3[CH2:71][CH2:70][N:69]([c:66]4[cH:65][cH:64][c:63]([C:61]#[N:62])[cH:68][n:67]4)[CH2:74][CH2:73]3)=[O:76])[CH2:47][CH2:48][CH:49]2[CH:50]([CH3:51])[NH:52][c:53]2[n:54][cH:55][c:56]([C:57]#[N:58])[cH:59][cH:60]2)[cH:42][cH:43]1Participants
4
