3-(4-Methyl-1-piperazine)propan-1-ol → 4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazoline

HRID 124044

Reaction equation

HRID 124044 reaction equation
[CH3:15][N:16]1[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][CH2:24][OH:25])[CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12>>[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:24][CH2:23][CH2:22][N:19]3[CH2:18][CH2:17][N:16]([CH3:15])[CH2:21][CH2:20]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12

Participants

3

Reactant 2

HCID 792083-(4-Methyl-1-piperazine)propan-1-olHCID 1357422514-Chloro-6-methoxyquinazolin-7-ol

Product 1

HCID 112450614-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazoline

Sources & evidence

ORD record
ord-e6dbaa3324e64aa3b62d763f71a9b1aa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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