2-Aminobenzimidazole → 3-[(1h-Benzimidazol-2-yl)amino]-3-oxopropan-1-amine

Reaction equation

C[C:2]1[C:16](C)=[CH:15][C:5]2[NH:6][C:7]([NH:9][C:10](=[O:14])[CH2:11][CH2:12][NH2:13])=[N:8][C:4]=2[CH:3]=1.NC1NC2C=CC=CC=2N=1>>[NH:6]1[C:5]2[CH:15]=[CH:16][CH:2]=[CH:3][C:4]=2[N:8]=[C:7]1[NH:9][C:10](=[O:14])[CH2:11][CH2:12][NH2:13]

Participants

Reactant 2

HCID 136242-Aminobenzimidazole

HCID 21912584HCID 21912584, compound

Product 1

HCID 219126013-[(1h-Benzimidazol-2-yl)amino]-3-oxopropan-1-amine

Procedure

Synthesis took place in analogy to the preparation of 26 starting from (1.60 g; 12 mmol) of 2-aminobenzimidazole. 1.20 g; ESI-MS [M+H+]=205.2

Workup

customSynthesis

Sources & evidence

ORD record: ord-26f91b26313f422c80bf7d20cfdfbb5d
Source dataset: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07125883B1

Reaction notes

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