Sulfamerazine → Silver Sulfamerazine

HRID 1246576

Reaction equation

HRID 1246576 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][N:5]=[C:6]([NH:8][S:9]([C:12]2[CH:13]=[CH:14][C:15]([NH2:18])=[CH:16][CH:17]=2)(=[O:11])=[O:10])[N:7]=1.[OH-].[Na+].[N+]([O-])([O-])=O.[Ag+:25]>O.[N+]([O-])(O)=O>[Ag:25].[CH3:1][C:2]1[CH:3]=[CH:4][N:5]=[C:6]([NH:8][S:9]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=2)(=[O:11])=[O:10])[N:7]=1

Participants

6

Reactant 3

HCID 5325Sulfamerazine2×HCID 14798Sodium HydroxideHCID 24470Silver Nitrate2×

Product 1

HCID 86591925Silver Sulfamerazine

Reagents, catalysts & solvents 2

HCID 944Nitric AcidCatalystHCID 962WaterSolvent2×

Procedure

Silver Sulfamerazine was prepared using 26.43 g sulfamerazine, 300 ml of water, 4.00 grams of NaOH warming to 70 degree C. until dissolved. 16.99 grams of silver nitrate in 300 grams of water with 1 drop of 10% nitric acid and warming to 70 degree C. The sulfamerazine solution was added to the silver nitrate solution with stirring. Silver sulfamerazine precipitated as a fine white powder. This was filtered and washed three times with water and dried overnight at 60 deg to give an off-white powder.

Workup

  1. customto 70 degree
  2. dissolutionuntil dissolved
  3. customSilver sulfamerazine precipitated as a fine white powder
  4. filtrationThis was filtered
  5. washwashed three times with water
  6. customdried overnight at 60 deg
  7. customto give an off-white powder

Sources & evidence

ORD record
ord-2dd6697f0d0c4c09b498644020fdc865
Source dataset
uspto-grants-2006_10
Patent number
US07129021B2

Linked notes

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