Sulfamethazine → silver 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH3:19])[N:5]=[C:6]([NH:8][S:9]([C:12]2[CH:13]=[CH:14][C:15]([NH2:18])=[CH:16][CH:17]=2)(=[O:11])=[O:10])[N:7]=1.[Ag:20].CC1C=CN=C(NS(C2C=CC(N)=CC=2)(=O)=O)N=1>>[CH3:19][C:4]1[N:5]=[C:6]([NH:8][S:9]([C:12]2[CH:13]=[CH:14][C:15]([NH2:18])=[CH:16][CH:17]=2)(=[O:11])=[O:10])[N:7]=[C:2]([CH3:1])[CH:3]=1.[Ag+:20]

Participants

Reactant 2

HCID 5327Sulfamethazine

HCID 86591925Silver Sulfamerazine

Product 1

HCID 44154837silver 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Procedure

Silver Sulfamethazine was prepared using 27.83 grams of sulfamethazine following procedure 1 (i.e. the procedure used for silver sulfamerazine) to give a fine white powder showing some crystallinity.

Workup

customto give a fine white powder

Sources & evidence

ORD record: ord-94620ae08aed4f8ab120d7696e029a7c
Source dataset: uspto-grants-2006_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07129021B2

Reaction notes

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