2-Indanylglycine → N-(3-benzoylthio-2(S)-methylpropionyl)-N-(2-indanyl)glycine

HRID 1248060

Reaction equation

HRID 1248060 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[NH:10][CH2:11][C:12]([OH:14])=[O:13].[C:15]([S:23][CH2:24][C@H:25]([CH3:29])[C:26](Cl)=[O:27])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:15]([S:23][CH2:24][C@@H:25]([CH3:29])[C:26]([N:10]([CH:2]1[CH2:3][C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH2:1]1)[CH2:11][C:12]([OH:14])=[O:13])=[O:27])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 99901132-IndanylglycineHCID 12878434(2S)-3-benzoylthio-2-methylpropionyl chloride

Product 1

HCID 13472314N-(3-benzoylthio-2(S)-methylpropionyl)-N-(2-indanyl)glycine

Procedure

By reacting N-(2-indanyl)glycine with 3-benzoylthio-2(S)-methylpropionyl chloride in a similar manner to that of Example 37, there is obtained N-(3-benzoylthio-2(S)-methylpropionyl)-N-(2-indanyl)glycine. Colorless needles.

Sources & evidence

ORD record
ord-5935358bf2e6450fbd31f2962ee712b5
Source dataset
uspto-grants-1985_06
Patent number
US04521607

Linked notes

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