Sodium borohydride → 2-(Imidazol-1-yl)-1-(thiazol-2-yl)ethanol
Reaction equation
[N:1]1([CH2:6][C:7]([C:9]2[S:10][CH:11]=[CH:12][N:13]=2)=[O:8])[CH:5]=[CH:4][N:3]=[CH:2]1.[BH4-].[Na+]>CO>[N:1]1([CH2:6][CH:7]([C:9]2[S:10][CH:11]=[CH:12][N:13]=2)[OH:8])[CH:5]=[CH:4][N:3]=[CH:2]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2-(Imidazol-1-yl)-1-(thiazol-2-yl)ethanone was reduced with sodium borohydride in methanol to give 2-(imidazol-1-yl)-1-(thiazol-2-yl)ethanol in 60% yield.
Sources & evidence
- ORD record
- ord-5100b9eb78d7477e9c400649ccaa3c35
- Source dataset
- uspto-grants-2002_01
- Patent number
- US06342765B1
Reaction notes
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