Ammonia → HCID 20137143, compound

Reaction equation

[CH3:1][NH:2][C:3](=S)[NH:4][C:5]1[CH:9]=[N:8][N:7]([CH2:10][CH2:11][CH2:12][CH2:13][C:14]#[N:15])[N:6]=1.[NH3:17]>>[CH3:1][N:2]=[C:3]([NH2:17])[NH:4][C:5]1[CH:9]=[N:8][N:7]([CH2:10][CH2:11][CH2:12][CH2:13][C:14]#[N:15])[N:6]=1

Participants

Reactant 2

HCID 222Ammonia

HCID 54138282HCID 54138282, compound

Product 1

HCID 20137143HCID 20137143, compound

Procedure

A solution of 5-[4-(3-methylthioureido)1,2,3-triazol-2-yl]valeronitrile in methanolic ammonia (6M; 15 ml.) was treated with mercuric oxide (1.1 g.) and tne mLxture stirred for 3 hours at room temperature. The resulting suspension was filtered through diatomaceous earth and the filtrate evaporated to give 5-[4-(2-methylguanidino)-1,2,3-triazol-2-yl]valeronitrile as a yellow oil.

Workup

filtrationThe resulting suspension was filtered through diatomaceous earth
customthe filtrate evaporated

Sources & evidence

ORD record: ord-52280a94928b44df9c533c8d4d2d65e5
Source dataset: uspto-grants-1988_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04748165

Reaction notes

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