Ethyl isothiocyanate → HCID 53787466, compound
Reaction equation
[NH2:1][C:2]1[CH:6]=[N:5][N:4]([CH2:7][CH2:8][CH2:9][CH2:10][C:11]#[N:12])[N:3]=1.[CH2:13]([N:15]=[C:16]=[S:17])[CH3:14]>C(#N)C>[CH2:13]([NH:15][C:16](=[S:17])[NH:1][C:2]1[CH:6]=[N:5][N:4]([CH2:7][CH2:8][CH2:9][CH2:10][C:11]#[N:12])[N:3]=1)[CH3:14]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 5-(4-amino-1,2,3-triazol-2-yl)valeronitrile (1.65 g.) in acetonitrile (6 ml.) was treated with ethylisothiocyanate (0.87 g.) and the solution stirred for 2.5 days then heated under reflux for 4.5 hours. Evaporation of the solvent gave 5-[4-(3-ethylthioureido)-1,2,3-triazol-2-yl]valeronitrile.
Workup
- temperaturethen heated
- temperatureunder reflux for 4.5 hours
- customEvaporation of the solvent
Sources & evidence
- ORD record
- ord-e82122b92bd14f68a638e6154bfec3c9
- Source dataset
- uspto-grants-1988_05
- Patent number
- US04748165
Reaction notes
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