Ethyl isothiocyanate → 1-Ethyl-3-[7-(3,4,5-trimethoxy-phenylamino)-[1,5]naphthyridin-2-yl]-thiourea
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH:13][C:14]2[CH:23]=[C:22]3[C:17]([CH:18]=[CH:19][C:20]([NH2:24])=[N:21]3)=[N:16][CH:15]=2)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].[CH2:25]([N:27]=[C:28]=[S:29])[CH3:26]>N1C=CC=CC=1>[CH2:25]([NH:27][C:28]([NH:24][C:20]1[CH:19]=[CH:18][C:17]2[C:22](=[CH:23][C:14]([NH:13][C:5]3[CH:6]=[C:7]([O:11][CH3:12])[C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=3)=[CH:15][N:16]=2)[N:21]=1)=[S:29])[CH3:26]Participants
4
Conditions
- Temperature
- 140 °C