2-Fluoro-3-(trifluoromethyl)phenol → 3-(4-Fluorophenyl)-2-[2-fluoro-3-(trifluoromethyl)phenoxy]pyrido[3,2-d]pyrimidin-4(3H)-one

HRID 125660

Reaction equation

HRID 125660 reaction equation
[Cl:1][c:2]1[n:3](-[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:4](=[O:12])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][cH:10][n:11]2.[F:20][c:21]1[c:22]([OH:31])[cH:23][cH:24][cH:25][c:26]1[C:27]([F:28])([F:29])[F:30]>>[c:2]1([O:31][c:22]2[c:21]([F:20])[c:26]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:24][cH:23]2)[n:3](-[c:13]2[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]2)[c:4](=[O:12])[c:5]2[c:6]([n:7]1)[cH:8][cH:9][cH:10][n:11]2

Participants

3

Reactant 2

HCID 27375862-Fluoro-3-(trifluoromethyl)phenolHCID 576141462-Chloro-3-(4-fluorophenyl)pyrido[3,2-d]pyrimidin-4(3H)-one

Product 1

HCID 576141423-(4-Fluorophenyl)-2-[2-fluoro-3-(trifluoromethyl)phenoxy]pyrido[3,2-d]pyrimidin-4(3H)-one

Sources & evidence

ORD record
ord-dddcc2311a9844fdad03d3dc6587ad76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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