HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lonidamine → ethyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lonidamine | HCID 39562 | — |
| Reactant | Tolnidamine | HCID 68679 | — |
| Reactant | ethyl 1-(4-chloro-2-methylbenzyl)-1H-indazole-3-carboxylate | HCID 67092644 | — |
| Product | ethyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate | HCID 11653177 | — |
Reaction Steps
The product was obtained using the method described for the preparation of compound 10a, but using as reagent 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid, prepared as described in J. Med. Chem. (1976) 19, 778-783, (0.4 mol) instead of 1-(4-chloro-2-methylbenzyl)-1H-indazole-3-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461194B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-a9aa5fe1388645489a8961e2b174bf24 |
| Source note | uspto-grants-2013_06 |