ethyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate → 2-[1-(2,4-dichlorobenzyl)-1H-indazol-3-yl]propan-2-ol

HRID 1256628Notes

Reaction equation

HRID 1256628 reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9]([C:16]([OH:19])([CH3:18])[CH3:17])=[N:8]2)=[C:4](C)[CH:3]=1.[Cl:23]C1C=C(Cl)C=CC=1CN1C2C(=CC=CC=2)C(C(OCC)=O)=N1>>[Cl:23][C:4]1[CH:3]=[C:2]([Cl:1])[CH:21]=[CH:20][C:5]=1[CH2:6][N:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([C:16]([OH:19])([CH3:18])[CH3:17])=[N:8]1

Participants

3

Reactant 2

HCID 11653177ethyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylateHCID 441993922-[1-(4-chloro-2-methylbenzyl)-1H-indazol-3-yl]propan-2-ol

Product 1

HCID 442178002-[1-(2,4-dichlorobenzyl)-1H-indazol-3-yl]propan-2-ol

Procedure

The product was obtained using the method described for the preparation of compound 10b, but using as starting material compound 11a (0.4 mol) instead of compound 10a.

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-1fe66d2f6d9345f780fbce9646275b6a
Source dataset
uspto-grants-2013_06
Patent number
US08461194B2

Reaction notes

Loading…